This paper takes on the challenge to integrate packaging in a concept of four-dimensional concurrent engineering (4DCE). The purpose is to explore a conceptual model and empirically evaluate the specific performance of packaging in interrelation with product and processes in the Supply Chain (SC). The objectives are to better understand the concepts of packaging logistics and logistics management in the SC. The conceptual model 4DCE is developed based on the three-dimensional concurrent engineering theories.The tool Packaging Scorecard is applied to evaluate the concurrent performance of packaging throughout the SC. The packaging system involves many actors that are integrated into the 4DCE framework with focus on interaction of SC and logistics in relation to packaging and product, with the overall aim to operate as effectively and efficiently as possible. In order to explore the potential of the 4DCE framework, empirical verification and testing of the concept has been carried out. The process has been done through multiple in-depth, action-oriented case studies in three different industries on the Swedish market. The case studies covered holistic aspects on the packaging system.The concept 4DCE contributes to packaging logistics theory by providing a framework for assessment incorporating complex and dynamic interactions between product, packaging, logistics and SC. Furthermore, the holistic packaging development concept is ensured by increasing knowledge of the packaging system and how it interacts with actors and performs to fulfil requirements along the SC. The 4DCE provides valuable data for packaging development processes in the cases, however there is a need for broader studies in different industries.