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Outcome prediction of enteral levodopa/carbidopa infusion in advanced Parkinson's disease
Dalarna University, School of Technology and Business Studies, Computer Engineering.ORCID iD: 0000-0003-0403-338X
Dalarna University, School of Technology and Business Studies, Computer Engineering.
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2006 (English)In: Parkinsonism & Related Disorders, ISSN 1353-8020, E-ISSN 1873-5126, Vol. 12, no 8, p. 509-513Article in journal (Refereed) Published
Abstract [en]

Two studies comparing intraduodenal infusion of a levodopa/carbidopa gel with oral treatments in advanced PD patients, demonstrated improvement in UPDRS scores and in frequent clinical ratings on a global treatment response scale. Further analysis of data from these studies was performed to find predictive factors related to degree of improvement with infusion. Pearson correlation coefficients between measures of improvement and baseline variables were calculated. Using data from one study, a prediction model was designed and was then evaluated using the other study’s data. Correlations were found indicating that patients with more severe symptoms at baseline were most improved after infusion.

Place, publisher, year, edition, pages
2006. Vol. 12, no 8, p. 509-513
Keywords [en]
outcome prediction, predictive model, predictive factor Parkinson, continous dopaminergic stimulation, improvement measure, infusion, levodopa
National Category
Clinical Medicine Computer and Information Sciences
Identifiers
URN: urn:nbn:se:du-1905DOI: 10.1016/j.parkreldis.2006.02.006ISI: 000243285100008PubMedID: 16731025OAI: oai:dalea.du.se:1905DiVA, id: diva2:519638
Available from: 2006-03-07 Created: 2006-03-07 Last updated: 2018-01-12Bibliographically approved

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Westin, Jerker

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