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Unsupervised learning from motion sensor data to assess the condition of patients with parkinson's disease
Dalarna University, School of Technology and Business Studies, Microdata Analysis.ORCID iD: 0000-0002-1548-5077
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2019 (English)Conference paper, Published paper (Refereed)
Abstract [en]

Parkinson’s disease (PD) is a chronic neurodegenerative disorder that predominantly affects the patient’s motor system, resulting in muscle rigidity, bradykinesia, tremor, and postural instability. As the disease slowly progresses, the symptoms worsen, and regular monitoring is required to adjust the treatment accordingly. The objective evaluation of the patient’s condition is sometimes rather difficult and automated systems based on various sensors could be helpful to the physicians. The data in this paper come from a clinical study of 19 advanced PD patients with motor fluctuations. The measurements used come from the motion sensors the patients wore during the study. The paper presents an unsupervised learning approach applied on this data with the aim of checking whether sensor data alone can indicate the patient’s motor state. The rationale for the unsupervised approach is that there was significant inter-physician disagreement on the patient’s condition (target value for supervised machine learning). The input to clustering came from sensor data alone. The resulting clusters were matched against the physicians’ estimates showing relatively good agreement. 

Place, publisher, year, edition, pages
2019. Vol. 11526, p. 420-424
Series
Lecture Notes in Computer Science, ISSN 0302-9743 ; 11526
Keywords [en]
Bradykinesia, Dyskinesia, Motion sensor, Objective evaluation, Parkinson’s disease, Patient monitoring, Unsupervised learning
National Category
Electrical Engineering, Electronic Engineering, Information Engineering
Research subject
Research Profiles 2009-2020, Complex Systems – Microdata Analysis
Identifiers
URN: urn:nbn:se:du-30569DOI: 10.1007/978-3-030-21642-9_52ISI: 000495606500052Scopus ID: 2-s2.0-85068314091ISBN: 9783030216412 (print)OAI: oai:DiVA.org:du-30569DiVA, id: diva2:1338382
Conference
17th Conference on Artificial Intelligence in Medicine, AIME 2019; Poznan; Poland; 26-29 June 2019
Available from: 2019-07-22 Created: 2019-07-22 Last updated: 2021-11-12Bibliographically approved

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Aghanavesi, Somayeh

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CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • chicago-author-date
  • chicago-note-bibliography
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf