This paper analyses the European Parliament in the light of agenda Europe 2020 with a specific focus on the transnational party groups. It starts with clarifying the legal and institutional framework for Europe 2020 and to what degree the European Parliament is involved in the agenda-setting stage, actual creation, decision process and implementation process. Thus, what have been the openings and possibilities for political entrepreneurship of the party groups and of individual members of Parliament? Secondly, it identifies the main issues around Europe 2020 which have been up for debate in the European Parliament. The main interest here lies in whether the conflicts concerns transnational ideological issues (like economic issues between Left and Right or between growth and sustainability) or domestic interests. Thirdly, it identifies examples of political entrepreneurship strategies among the party groups and their individual members. It is important to remember that the European party families are present in each EU-institution. Consequently, there is room for informal influence may on fellow party sympathisers in other key EU institutions like the Commission or the Council.