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Equally Good Neurological, Growth, and Health Outcomes up to 6 Years of Age in Moderately Preterm Infants Who Received Exclusive vs. Fortified Breast Milk-A Longitudinal Cohort Study
Dalarna University, School of Health and Welfare, Caring Science/Nursing. Centre for Clinical Research Dalarna, Uppsala University, Falun; Department of Pediatrics, Falu Hospital, Falun.ORCID iD: 0000-0002-3460-7500
Department of Women's and Children's Health, Uppsala University, Uppsala.
Division of Neonatology, Department of Pediatrics, University Medical Center of the Johannes Gutenberg, University Mainz, Mainz, Germany; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm.
Department of Women's and Children's Health, Karolinska Institutet, Stockholm.
2023 (English)In: Nutrients, E-ISSN 2072-6643, Vol. 15, no 10, article id 2318Article in journal (Refereed) Published
Abstract [en]

Moderately preterm infants (32-36 weeks of gestational age) have an increased risk of worse health and developmental outcomes compared to infants born at term. Optimal nutrition may alter this risk. The aim of this study was to investigate the neurological, growth, and health outcomes up to six years of age in children born moderately preterm who receive either exclusive or fortified breast milk and/or formula in the neonatal unit. In this longitudinal cohort study, data were collected for 142 children. Data were collected up to six years of age via several questionnaires containing questions about demographics, growth, child health status, health care visits, and the Five to Fifteen Questionnaire. Data on the intake of breast milk, human milk fortification, formula, and growth during hospitalization were collected from the children's medical records. No statistically significant differences in neurological outcomes, growth, or health at six years of age were found between the two groups (exclusive breast milk, n = 43 vs. fortified breast milk and/or formula, n = 99). There is a need for research in larger populations to further assess potential effects on health and developmental outcomes when comparing the use of exclusive versus fortified breast milk for moderately preterm infants during neonatal hospitalization.

Place, publisher, year, edition, pages
2023. Vol. 15, no 10, article id 2318
Keywords [en]
development, exclusive breast milk, growth, health, human milk fortification, moderately preterm infant
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:du-46102DOI: 10.3390/nu15102318ISI: 000998141700001PubMedID: 37242201Scopus ID: 2-s2.0-85160352171OAI: oai:DiVA.org:du-46102DiVA, id: diva2:1760364
Available from: 2023-05-30 Created: 2023-05-30 Last updated: 2023-08-28Bibliographically approved

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Ericson, Jenny

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