Dalarna University's logo and link to the university's website

du.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • chicago-author-date
  • chicago-note-bibliography
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Acute exercise as active inference in chronic musculoskeletal pain, effects on gait kinematics and muscular activity in patients and healthy participants: a study protocol for a randomised controlled laboratory trial
Dalarna University, School of Health and Welfare, Sport and Health Science. Dalarna University, School of Health and Welfare, Care Sciences.ORCID iD: 0000-0001-8356-4669
Dalarna University, School of Health and Welfare, Care Sciences. Dalarna University, School of Health and Welfare, Medical Science.ORCID iD: 0000-0002-3843-0407
Dalarna University, School of Health and Welfare, Medical Science.ORCID iD: 0000-0002-6923-7140
Dalarna University, School of Information and Engineering, Informatics.ORCID iD: 0000-0003-4812-4988
Show others and affiliations
2023 (English)In: BMJ Open, E-ISSN 2044-6055, Vol. 13, no 5, article id e069747Article in journal (Refereed) Published
Abstract [en]

Introduction

Chronic musculoskeletal pain is a highly prevalent, complex and distressing condition that may negatively affect all domains of life. In view of an active inference framework, and resting on the concept of allostasis, human movement per se becomes a prerequisite for health and well-being while chronic pain becomes a sign of a system unable to attenuate an allostatic load. Previous studies on different subgroups of chronic pain conditions have demonstrated alterations in gait kinematics and muscle activity, indicating shared disturbances in the motor system from long-term allostatic load. We hypothesise that such alterations exist in heterogenous populations with chronic musculoskeletal pain, and that exposure to acute and controlled exercise may attenuate these alterations. Therefore, the main aim of this study is to investigate the acute effects of exercise on gait kinematics and activity of the back and neck muscles during diverse walking conditions in patients with chronic musculoskeletal pain compared with a reference sample consisting of healthy participants.

Methods and analysis

This two-sample two-armed parallel randomised controlled laboratory trial will include 40 participants with chronic musculoskeletal pain (>3 months) and 40 healthy participants. Participants will be randomly allocated to either 30 min of aerobic exercise or rest. Primary outcomes are gait kinematics (walking speed, step frequency, stride length, lumbar rotation, gait stability) and muscular activity (spatial and temporal) of the back and neck during diverse walking conditions. Secondary outcomes are variability of gait kinematics and muscle activity and subjective pain ratings assessed regularly during the trial.

Ethics and dissemination

The study has been approved by the Regional Ethics Review Board in Uppsala, Sweden (#2018/307). Findings will be disseminated via conference presentations, publications in peer-reviewed journals and engagement with patient support groups and clinicians.

Trial registration number

NCT03882333.

Place, publisher, year, edition, pages
2023. Vol. 13, no 5, article id e069747
National Category
Clinical Medicine
Research subject
Health and Welfare, Fysisk aktivitet, rörelsekontroll och muskelaktivitet hos personer med långvarig smärta
Identifiers
URN: urn:nbn:se:du-46116DOI: 10.1136/bmjopen-2022-069747ISI: 001007725500001PubMedID: 37258077Scopus ID: 2-s2.0-85160705639OAI: oai:DiVA.org:du-46116DiVA, id: diva2:1761922
Funder
Dalarna University, No grant numberSwedish Research Council, 2015-02512Forte, Swedish Research Council for Health, Working Life and Welfare, 2017-00177Dalarna University, No grant numberSwedish Research Council, 2015-02512Forte, Swedish Research Council for Health, Working Life and Welfare, 2017-00177Available from: 2023-06-02 Created: 2023-06-02 Last updated: 2023-08-28Bibliographically approved

Open Access in DiVA

Acute exercise as active inference in chronic musculoskeletal pain, effects on gait kinematics and muscular activity in patients and healthy participants: a study protocol for a randomised controlled laboratory trial(1874 kB)82 downloads
File information
File name FULLTEXT01.pdfFile size 1874 kBChecksum SHA-512
961a531c7f5ea16cd61ca10a5f64b5c7b78e8dec7aec3a11f2cffae89206e8bacef10afc49e51795e0d4adc4561b7fa41e96b05cdfdec8b2f55c3bed1862119e
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Westergren, JensSjöberg, VeronicaVixner, LindaNyberg, Roger G.Monnier, AndreasÄng, Björn

Search in DiVA

By author/editor
Westergren, JensSjöberg, VeronicaVixner, LindaNyberg, Roger G.Moulaee Conradsson, DavidMonnier, AndreasLoMartire, RiccardoEnthoven, PaulÄng, Björn
By organisation
Sport and Health ScienceCare SciencesMedical ScienceInformatics
In the same journal
BMJ Open
Clinical Medicine

Search outside of DiVA

GoogleGoogle Scholar
Total: 82 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 568 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • chicago-author-date
  • chicago-note-bibliography
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf