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Background: Integrating mobile health (mHealth) tools into preconception care (PCC) for individuals at risk for feto-maternal complications (RfFMC) offers the potential of improving sexual and reproductive health and rights globally. mHealth tools provide tailored information, self-management tools, and real-time support, addressing unique challenges faced by high-risk individuals.

Aim: To identify the specific needs and expectations of both targeted clients and HCPs towards PCC mHealth tools designed for individuals at RfFMC. Through assessing barriers and assets, and users’ attitudes and perceptions, it further aims at detecting the strengths and limitations inherent in their application within high-risk PCC.

Methodology: An integrative review of 15 empirical studies with mixed designs was conducted. Systematic searches in PubMed, CINAHL, and Web of Science, followed by quality assessment using the mixed-method appraisal tool, were employed. Data were analysed using the constant comparison method.

Results: A user-centric perspective on mHealth tools revealed the need for tailored features, user-friendly interfaces, culturally sensitive content, and social support. Strengths included positive health behaviour impact and accessibility, while challenges involved limited engagement and technical difficulties.

Conclusion: This review underscores the potential of user-centred mHealth tools in improving PCC for individuals at RfFMC. Identified needs align with predictors for self-efficacy, suggesting pathways for empowering health management through mHealth solutions. Addressing various factors is crucial for optimal effectiveness and global applicability.