du.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
A fuzzy logic controller for intestinal levodopa infusion in Parkinson’s disease
Dalarna University, School of Technology and Business Studies, Computer Engineering.
2010 (English)Independent thesis Basic level (degree of Bachelor)Student thesis
Abstract [en]

The aim of this work is to evaluate the fuzzy system for different types of patients for levodopa infusion in Parkinson Disease based on simulation experiments using the pharmacokinetic-pharmacodynamic model. Fuzzy system is to control patient’s condition by adjusting the value of flow rate, and it must be effective on three types of patients, there are three different types of patients, including sensitive, typical and tolerant patient; the sensitive patients are very sensitive to drug dosage, but the tolerant patients are resistant to drug dose, so it is important for controller to deal with dose increment and decrement to adapt different types of patients, such as sensitive and tolerant patients. Using the fuzzy system, three different types of patients can get useful control for simulating medication treatment, and controller will get good effect for patients, when the initial flow rate of infusion is in the small range of the approximate optimal value for the current patient’ type.

Place, publisher, year, edition, pages
2010.
Keyword [en]
Parkinson Disease, fuzzy controller, pharmacokinetic-pharmacodynamic model, levodopa, infusion, dose titration
Identifiers
URN: urn:nbn:se:du-4727OAI: oai:dalea.du.se:4727DiVA: diva2:518837
Uppsok
Technology
Supervisors
Available from: 2010-05-24 Created: 2010-05-24 Last updated: 2012-04-24Bibliographically approved

Open Access in DiVA

fulltext(819 kB)334 downloads
File information
File name FULLTEXT01.pdfFile size 819 kBChecksum SHA-512
391bd06cda7dc6da509207a19b5c91dd26f939dd2432dcf728e41636f22a20fadafe3b7101e48559a4a975c3316fadcc180f47ebeb9b2eeb29a516ecd1429d96
Type fulltextMimetype application/pdf

By organisation
Computer Engineering

Search outside of DiVA

GoogleGoogle Scholar
Total: 334 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 362 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf