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A home environment test battery for status assessment in patients with motor fluctuations
Dalarna University, School of Technology and Business Studies, Computer Engineering.ORCID iD: 0000-0003-0403-338X
Dalarna University, School of Technology and Business Studies, Computer Engineering.
2006 (English)In: European Journal of Neurology, Glasgow, UK, 2006, Vol. 13, 213-14 p.Conference paper, Published paper (Refereed)
Abstract [en]

Background and aims Evaluating status in patients with motor fluctuations is complex and occasional observations/measurements do not give an adequate picture as to the time spent in different states. We developed a test battery to assess advanced Parkinson patients' status consisting of diary assessments and motor tests. This battery was constructed and implemented on a handheld computer with built-in mobile communication. In fluctuating patients, it should typically be used several times daily in the home environment, over periods of about one week. The aim of this battery is to provide status information in order to evaluate treatment effects in clinical practice and research, follow up treatments and disease progression and predict outcome to optimize treatment strategy. Methods Selection of diary questions was based on a previous study with Duodopa® (DIREQT). Tapping tests (with and without visual cueing) and a spiral drawing test were added. Rapid prototyping was used in development of the user interface. An evaluation with two pilot patients was performed before and after receiving new treatments for advanced disease (one received Duodopa® and one received DBS). Speed and proportion missed taps were calculated for the tapping tests and entropy of the radial drawing velocity was calculated for the spiral tests. Test variables were evaluated using non-parametric statistics. Results Post-treatment improvement was detected in both patients in many of the test variables. Conclusions Although validation work remains, preliminary results are promising and the test battery is currently being evaluated in a long-term health economics study with Duodopa® (DAPHNE).

Place, publisher, year, edition, pages
Glasgow, UK, 2006. Vol. 13, 213-14 p.
Keyword [en]
Parkinson, movement disorder, fluctuation, test battery, status assessment, e-diary, motor test
Identifiers
URN: urn:nbn:se:du-1915OAI: oai:dalea.du.se:1915DiVA: diva2:521575
Conference
10th Congress of the European Federation of Neurological Societies , Glasgow, UK, Sept 2-5, 2006
Available from: 2006-03-07 Created: 2006-03-07 Last updated: 2015-06-01Bibliographically approved

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CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf