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Improving survival and neurologic function for younger age groups after out-of-hospital cardiac arrest in Sweden: a 20-year comparison
Lund Univ, Dept Pediat Anesthesia & Intens Care, Skane Univ Hosp, Lund, Sweden..
Dalarna University, School of Education, Health and Social Studies, Medical Science. Univ Dalarna, Sch Hlth & Social Sci, Karolinska Inst, Inst Med, Falun, Sweden..
Soder Sjukhuset, Karolinska Inst, Dept Clin Sci & Educ, Dept Educ,Cardiol Sect, Stockholm, Sweden..
Karolinska Univ Hosp, Astrid Lindgrens Childrens Hosp, Det Pediat Anesthesia & Intens Care, Stockholm, Sweden..
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2015 (English)In: Pediatric Critical Care Medicine, ISSN 1529-7535, E-ISSN 1947-3893, Vol. 16, no 8, 750-757 p.Article in journal (Refereed) PublishedText
Abstract [en]

Objective: To describe changes in the epidemiology of out-of-hospital cardiac arrest in Sweden with the emphasis on the younger age groups.

Design: Prospective observational study. Setting: Sweden.

Patients: Patients were recruited from the Swedish Registry of Cardiopulmonary Resuscitation from 1990 to 2012. Only non-crew-witnessed cases were included.

Intervention: Cardiopulmonary resuscitation.

Measurement and Main Results: The endpoint was 30-day survival. Cerebral function among survivors was estimated according to the cerebral performance category scores. In all, 50,879 patients in the survey had an out-of-hospital cardiac arrest, of which 1,321 (2.6%) were 21 years old or younger and 1,543 (3.0%) were 22-35 years old. On the basis of results from 2011 and 2012, we estimated that there are 4.9 cases per 100,000 person-years in the age group 0-21 years. The highest survival was found in the 13- to 21-year age group (12.6%). Among patients 21 years old or younger, the following were associated with an increased chance of survival: increasing age, male gender, witnessed out-of-hospital cardiac arrest, ventricular-fibrillation, and a short emergency medical service response time. Among patients 21 years old or younger, there was an increase in survival from 6.2% in 1992-1998 to 14.0% in 2007-2012. Among 30-day survivors, 91% had a cerebral performance category score of 1 or 2 (good cerebral performance or moderate cerebral disability) at hospital discharge.

Conclusions: In Sweden, among patients 21 years old or younger, five out-of-hospital cardiac arrests per 100,000 person-years occur and survival in this patient group has more than doubled during the past two decades. The majority of survivors have good or relatively good cerebral function.

Place, publisher, year, edition, pages
2015. Vol. 16, no 8, 750-757 p.
Keyword [en]
children, out-of-hospital cardiac arrest, outcome
National Category
Clinical Medicine
Research subject
Health and Welfare
URN: urn:nbn:se:du-21203DOI: 10.1097/PCC.0000000000000503ISI: 000369708000016PubMedID: 26218255OAI: oai:DiVA.org:du-21203DiVA: diva2:909043
Available from: 2016-03-04 Created: 2016-03-04 Last updated: 2016-03-04Bibliographically approved

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