This paper responds to previous calls for a deeper sociotechnical understanding of Internet of Things (IoT) adoption within healthcare. Through a systematic literature review, it synthesizes existing empirical research on the factors influencing IoT adoption, identifying 94 distinct factors grouped into 24 themes. By leveraging sociotechnical systems theory, the paper thoroughly analyzes these factors and proposes a specialized sociotechnical systems framework tailored specifically to IoT adoption in healthcare settings. This study underscores the current dearth of empirical research in this area and emphasizes the need for more studies, particularly those focused on the actual adoption processes of IoT solutions in healthcare contexts. By addressing these gaps, the review aims to significantly contribute to the literature, offering a novel sociotechnical perspective on IoT adoption that complements and enriches prior reviews that have predominantly focused on technical aspects. © 2024 The Authors