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This article presents an in-depth analysis of the current status of glass-ceramics in piezocatalysis and proposes potential avenues for future research in this field. Glass ceramics are a type of heterogeneous material that exhibits a combination of properties from both glass and crystalline phases. This unique characteristic makes them highly versatile and applicable in a diverse range of fields. The review commences by examining the historical importance of glass as a versatile substance that has been utilized since ancient times. The review delves deeper into the various applications of glass-ceramics, with a specific focus on their utilization in the area of piezocatalysis for environmental remediation. Piezocatalysis is a promising technology that employs mechanical energy to facilitate catalytic reactions. The utilization of glass-ceramics as piezocatalysts has exhibited potential in the field of environmental remediation. Prior research has examined photocatalytic glass ceramics; however, this review underscores the dearth of published studies on piezocatalytic glass-ceramics in the context of environmental remediation. The article examines the efficacy of glass-ceramic piezocatalysts in degrading organic pollutants and purifying water, while also exploring their potential for antibacterial purposes.