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Validation of the Holmlund-Grooten sub-maximal arm crank ergometer-test for estimating peak oxygen uptake in wheelchair users with Spinal Cord Injury
Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Huddinge; .
Dalarna University, School of Health and Welfare, Physiotherapy. Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Huddinge; .ORCID iD: 0000-0002-1697-9781
2026 (English)In: PLOS ONE, E-ISSN 1932-6203, Vol. 21, no 4, article id e0344188Article in journal (Refereed) Published
Abstract [en]

STUDY DESIGN: Cross-sectional validity study.

OBJECTIVES: To determine the criterion validity, Standard Error of the Measurement (SEM) and Minimal Detectable Change (MDC), of a newly developed submaximal test (Holmlund-Grooten test) for estimating the peak oxygen consumption in wheelchair users with motor-complete Spinal Cord Injury (mcSCI).

SETTINGS: Outpatient rehabilitation centre in Stockholm, Sweden.

METHODS: Peak and submaximal oxygen uptake (VO2) was measured using indirect calorimetry. A backward linear regression model, including heart rate, power output, and several demographic variables, was used to predict absolute VO2peak.

RESULTS: In total, 63 individuals (16 females) with mcSCI were included. The final prediction model included four significant (p < 0.05) variables (sex, injury level, heart rate, power output) that were able to predict absolute VO2peak (adjusted R2 = 0.77). The Holmlund-Grooten test showed excellent criterion validity (ICC = 0.88; 95%CI 0.83-0.94), SEM = 0.05 L·min-1 and MDC = 0.13 L·min-1. No adverse events were reported. We provide an Excel file that calculates VO2peak based on the Holmlund-Grooten model for males and females and tetra- and paraplegia for clinical use.

CONCLUSION: The Holmlund-Grooten test is a valid submaximal test for estimating VO₂peak in wheelchair users with SCI and can be easily implemented in clinical settings.

Place, publisher, year, edition, pages
2026. Vol. 21, no 4, article id e0344188
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Health Sciences
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URN: urn:nbn:se:du-53292DOI: 10.1371/journal.pone.0344188ISI: 001731837000027PubMedID: 41920832Scopus ID: 2-s2.0-105034661220OAI: oai:DiVA.org:du-53292DiVA, id: diva2:2051414
Available from: 2026-04-08 Created: 2026-04-08 Last updated: 2026-05-07Bibliographically approved

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