Sweden has over the last few decades increasingly become a multilingual society, with the result that many Swedish classrooms are multilingual and multicultural. This study investigates how compulsory school teachers, in a number of schools in a county in central Sweden work with multilingual students’ vocabulary development in English. It also explores the teachers’ attitudes towards working with these students. A qualitative interview study with semi-structured questions was carried out with six English teachers teaching in years 7-9, at four schools in three different cities in the same county. The study shows that the teachers use the target language, English, more when they teach a multilingual class and explain more words in English. Nevertheless, according to the results, Swedish still plays an important role in the EFL classroom, which can be challenging for those with insufficient Swedish skills, especially when using Swedish textbooks and glossary lists. Based on these results, further research regarding how to raise multilingual awareness and how to teach English without relying on Swedish as the common, first language of the classroom, is recommended.